J Altern Complement Med. 2018 May 9. doi: 10.1089\/acm.2017.0153. [Epub ahead of print]\nRanjbar M1,2, Salehi A2, Rezaeizadeh H3, Zarshenas MM4,5, Sadeghniiat-Haghighi K6, Mirabzadeh M7, Firoozabadi A2,8.<\/p>\n
Abstract<\/strong> OBJECTIVES:<\/strong> DESIGN AND SETTING:<\/strong> INTERVENTIONS:<\/strong> OUTCOME MEASURES:<\/strong> RESULTS:<\/strong> CONCLUSIONS:<\/strong> KEYWORDS:<\/strong> J Altern Complement Med. 2018 May 9. doi: 10.1089\/acm.2017.0153. [Epub ahead of print] Ranjbar M1,2, Salehi A2, Rezaeizadeh H3, Zarshenas MM4,5, Sadeghniiat-Haghighi K6, Mirabzadeh M7, Firoozabadi A2,8. Abstract BACKGROUND: Insomnia is a prevalent sleep disorder that has not been well managed thus far. There are numerous medicaments for treatment of insomnia, but they have undesirable …<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[52],"tags":[],"class_list":["post-899","post","type-post","status-publish","format-standard","","category-52"],"_links":{"self":[{"href":"https:\/\/iransleep.com\/fa\/wp-json\/wp\/v2\/posts\/899","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/iransleep.com\/fa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/iransleep.com\/fa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/iransleep.com\/fa\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/iransleep.com\/fa\/wp-json\/wp\/v2\/comments?post=899"}],"version-history":[{"count":1,"href":"https:\/\/iransleep.com\/fa\/wp-json\/wp\/v2\/posts\/899\/revisions"}],"predecessor-version":[{"id":900,"href":"https:\/\/iransleep.com\/fa\/wp-json\/wp\/v2\/posts\/899\/revisions\/900"}],"wp:attachment":[{"href":"https:\/\/iransleep.com\/fa\/wp-json\/wp\/v2\/media?parent=899"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/iransleep.com\/fa\/wp-json\/wp\/v2\/categories?post=899"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/iransleep.com\/fa\/wp-json\/wp\/v2\/tags?post=899"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nBACKGROUND:<\/strong>
\nInsomnia is a prevalent sleep disorder that has not been well managed thus far. There are numerous medicaments for treatment of insomnia, but they have undesirable side effects that make herbal medicine a more viable option.<\/p>\n
\nThe effectiveness of a combination of Melissa officinalis L. (dry powder) and Nepeta menthoides Boiss. & Buhse (freeze-dried aqueous extract) on insomnia was evaluated.<\/p>\n
\nInsomniacs who met the entry criteria participated in a triple-blind randomized placebo-controlled clinical trial at the Persian Medicine (PM) clinic in Tehran.<\/p>\n
\nThe subjects received either 1000 mg of M. officinalis plus 400 mg N. menthoides or a placebo nightly for four weeks in accordance with prescriptions from the pharmaceutical manuscripts on PM and the results of previous studies.<\/p>\n
\nThe Pittsburgh Sleep Quality Index (PSQI), sleep diary, and Insomnia Severity Index (ISI) were used for assessment of insomnia.<\/p>\n
\nComparison of the treatment and placebo groups showed a significant decrease in the mean difference of ISI (4.97\u2009\u00b1\u2009\u06f4\u066b\u06f6\u06f9 vs. 1.60\u2009\u00b1\u2009\u06f3\u066b\u06f7\u06f0; p\u2009=;\u2009\u06f0\u066b\u06f0\u06f0\u06f2) and total PSQI (4.14\u2009\u00b1\u2009\u06f3\u066b\u06f6\u06f9 vs. 1.42\u2009\u00b1\u2009\u06f2\u066b\u06f8\u06f1; p\u2009=\u2009\u06f0\u066b\u06f0\u06f0\u06f1) scores in the treatment group. A significant increase was also observed in total sleep time of treatment group (p\u2009<\u2009\u06f0\u066b\u06f0\u06f0\u06f1) based on the sleep diary.<\/p>\n
\nA combination of M. officinalis and N. menthoides Boiss. & Buhse could be an alternative sleep improvement therapy.<\/p>\n
\nMelissa officinalis; Nepeta menthoides; Persian Medicine; herbal medicine; insomnia; traditional medicine<\/p>\n","protected":false},"excerpt":{"rendered":"